Manufacturing /

Below you can find more information about our manufacturing

FACTORY NO. 4 (China)

It is an integrated chemistry CRO and CMO and focuses on developing pharmaceutical intermediates, peptide, cosmetic ingredients and dietary supplement ingredients, from lab scale to full scale manufacturing. After years of operation, our technological management team consists of experienced Ph.D. and M.S. who are familiar with the industry. They are dedicated to provide the global biotechnology and pharmaceutical industries with professional chemistry services. We own 53,820 sft total standing alone R&D building equipped with 13 synthetic labs, 1 kilo lab and 1 analytical lab. Our R&D building is equipped with Bruker 400MH NMR, Agilent 1200 HPLC, Analytical LCMS, Preparative LCMS, GCMS, Microwave synthesizers and other modern equipments. We have two cooperative plants with reactors from 50L to 5000L, low temperature vessels (-80℃) and high pressure and temperature vessels (12MPa, 250℃). Our compounds can be scaled up to tons in our manufacturing base with some other equipments, such as rectification column, muti-function workshop, clean workshop and so on.

Product List:

Intermediates of Enzalutamide (Indication: Prostate cancer)


CFP8131
CFP8133

143782-23-4
1289942-66-0

4-cyano-3-trifluoromethylphenylisothiocyanate
2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid


Intermediates of Apixaban (Indication: Venous thrombosis)


CFP8051
CFP8053
CFP8054
CFP8055
CFP8056
CFP8058

503615-03-0
536759-91-8
503614-91-3
27143-07-3
545445-44-1
536760-29-9

3-morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one Ethyl1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1Hpyrazolo[3,4-c]pyridine-3-carboxylate
Ethyl1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7- tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Ethyl2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
3-morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one
3-chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one


Intermediates of Rivaroxaban (Indication: Deep vein thrombosis and pulmonary embolism)


CFP8161
CFP8162

898543-06-1
446292-08-6

(S)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride
(S)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione


Intermediates of Avanafil (Indication: Erectile dysfunction)


CFP8081
CFP8082
CFP8084

41965-95-1
5909-24-0
372118-67-7

((3-chloro-4-methoxyphenyl)methanaminehydrochloride
Ethyl 4-chloro-2-methylthiopyrimidine 5-carboxylate
pyrimidin-2-ylmethanamine hydrochloride


Intermediates of Moxifloxacin (Indication: antibacterial activity)


CFP8171
CFP8172
CFP8173

112811-71-9
112811-72-0
151213-42-2

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acidethyl ester
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
(S,S)-2,8-Diazabicyclo[4,3,0]nonane


Intermediates of Sitagliptin (Indication: Type 2 diabetes mellitus)


CFP8181
CFP8182

762240-92-6
764667-65-4

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one


Intermediates of Vildagliptin (Indication: Type 2 diabetes mellitus)


CFP8191

702-82-9

3-Amino-1-hydroxyadamantane


Intermediates of Trelagliptin (Indication: Type 2 diabetes mellitus)


CFP8121
CFP8122

334618-23-4
865759-24-6

(R)-piperidin-3-ylamine dichloride
2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4- fluorobenzonitrile


Intermediates of Lurasidone (Indication: Schizophrenia)


Cmpd ID

CAS

Name

CFP8012
CFP8013
CFP8123
CFP8124

14805-29-9
46022-05-3
4318-56-3
421552-12-7

(3aR,4S,7R,7aS) 4,7-methano-1Hisoindole- 1,3(2H)- dione
(1R,2R)-cyclohexane-1,2-dicarboxylic acid
6-Chloro-3-methyluracil
2-(Bromomethyl)-4-fluorobenzonitrile


Intermediates of Alogliptin (Indication: Type 2 diabetes mellitus)


CFP8121
CFP8201
CFP8123

334618-23-4
865758-96-9
4318-56-3

(R)-piperidin-3-ylamine dichloride
2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h) pyriMidinyl)Methyl]benzonitrile
6-Chloro-3-methyluracil