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INTERMEDIATES

CAS NO.

Lisinopril Intermediates

N-6-Trifluoro acetyl-L-Lysine
N2-[(1S)-ethoxycarbonyl-3-phenylpropy]-N6-trifluoroacetyl-L-lysine
N2-[(1S)-ethoxycarbonyl-3-phenylpropyl]-N6-trifluoroacetyl-L-lysine-L-proline

10009-20-8
116169-90-5
103300-91-0

Risperidone intermediates

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride
6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
4-(2,4-Difluorobenzoyl)piperidine hydrochloride
3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1, 2-a]-pyrimidin-4-one
3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1, 2-a]-pyrimidin-4-one hydrochloride
(Z)-(2,4-difluorophenyl)-4-piperidinyl-Methanone oxime

84163-13-3
84163-77-9
106266-04-0
63234-80-0
93076-03-0
691007-05-3

Paliperidone Intermediates

2-Amino-3-benzyloxypyridine
9-(benzyloxy)-3-(2-chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

24016-03-3
147687-17-0
130049-82-0

Enalapril Intermediates

N-[(1S)-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine
N-[(1S)-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl carboxyanhydride

82717-96-2
84793-24-8

Quinapril Intermediate

Benzyl (S)-(-)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate p-toluenesulfonic acid salt
Quinapril benzyl ester maleate

24077497-97-3
82586-54-7

Sitagliptin Intermediate

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine

762240-92-6
486460-20-2

Rivaroxaban Intermediates

5-Chlorothiophene-2-carboxylicacid
4-(4-Aminophenyl)morpholin-3-one
(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one
(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride

24065-33-6
438056-69-0
446292-10-0
898543-06-1

Erlotinib Intermediate

3-Aminophenylacetylene

54060-30-9

Clopidogrel Intermediate

2-Thiopheneethanol
2-(2-Thienyl)ethyl 4-methylbenzenesulfonate
D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride

5402-55-1
40412-06-4
141109-19-5

Ketotifen

10-Methoxy-4H-benzo[4,5]cycloheta[1,2-b]thiophen-4-one

59743-84-9

Benazepril

3-(S)-amino-1-tertbutyloxycarbonylmethyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one

109010-60-8

Paroxetine

4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine
(3S,4R)-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

109887-53-8
105812-81-5

Brinzolamide

6-Chloro-2,3-dihydro-4H-thieno[3,2-e][1,2]thiazin-4-one 1,1-dioxide

174139-69-6

Duloxetine

(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine

132335-44-5

Pimozidete

1-(Piperidin-4-yl)-1,3-dihydrobenzoimidazol-2-one

20662-53-7

Crizotinib

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

877399-74-1

Atazanavir

tert-butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate

98904-85-7

Febuxostat

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
4-hydroxythiobenzamide

144060-53-7
161798-02-3
161798-03-4
161798-01-2
161797-99-5
25984-63-8

Tolvaptan

N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
2-Methyl-4-(2-methylbenzoylamino)benzoic acid
2-Methyl-4-nitrobenzoic acid
5-Chloro-2-nitrobenzoic acid

137973-76-3
160129-45-3
317374-08-6
1975-51-5
2516-95-2

Roflumilast

3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid
3,5-Dichloro-4-Amino Pyridine
4-(Difluoromethoxy)-3-(cyclopropylmethoxy)benzaldehyde
3-Cyclopropylmethoxy-4-Hydroxybenzaldehyde
4-Difluoromethoxy-3-hydroxybenzaldehyde

162401-62-9
22889-78-7
151103-09-2
25934-52-5
151103-08-1

Agomelatine

2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride
7-Methoxy-3,4-dihydro-1-naphthalenylacetonitrile
7-Methoxy-1-naphthylacetonitrile

139525-77-2
861960-34-1
138113-08-3

Iloperidone

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride
1-[4-(3-Chloropropoxy)-3-methoxyphenyl]ethanone

84163-13-3
58113-30-7

Tadalafil

D(+)-Tryptophan
D-Tryptophan methyl ester hydrochloride
(1r,3r)-methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9h-pyrido[3,4-b]indole-3-carboxylate
(1R,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-Pyrido[3,4-B]-indole-3-carboxylate hydrochloride

153-94-6
14907-27-8
171489-59-1
171752-68-4

Avanafil

4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester
5-PyriMidinecarboxylicacid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester
(S)-4-(3-chloro-4-MethoxybenzylaMino)-5-carboxy-2-(2-hydroxyMethyl-1-pyrrolidinyl)pyriMidine
3-chloro-4-methoxybenzylamine hydrochloride
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
2-aminomethylpyrimidine hydrochloride

330785-81-4
330785-83-6
330785-84-7
41965-95-1
5909-24-0
372118-67-7

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